Florian Krammer. Correlates of protection from SARS-CoV-2 infection. Lancet 2021 online
The findings of the authors suggest that infection and the development of an antibody response provides protection similar to or even better than currently used SARS-CoV-2 vaccines. Although antibodies induced by SARS-CoV-2 infection are more variable and often lower in titre than antibody responses induced after vaccination, this observation does make sense considering current SARS-CoV-2 vaccines induce systemic immune responses to spike proteins while natural infection also induces mucosal immune responses and immune responses against the many other open reading frames encoded by the approximately 29 900 nucleotides of SARS-CoV-2 …
Lancet, 9 kwietnia 2021