Gianfranco Parati i wsp. Adherence to Single-Pill Versus Free-Equivalent Combination Therapy in Hypertension. A Systematic Review and Meta-Analysis. Hypertension 2021 online
Systolic BP (mean difference, −3.99 [95% CI, −7.92 to −0.07]; P=0.05) and diastolic BP (−1.54 [95% CI, −2.67 to −0.41]; P=0.0076) were both significantly reduced with SPC therapy compared with FEC therapy at week 12. SPC therapy leads to improved adherence and persistence compared with FEC therapy and may lead to better BP control in patients with hypertension.
4 stycznia 2020