Baris Gencer i wsp. Efficacy and safety of lowering LDL cholesterol in older patients: a systematic review and meta-analysis of randomised controlled trials. Lancet 2020 online (dostępny pełen tekst)
Implications of all the available evidence:
Life expectancy for patients aged 75 years in high-income countries is expected to be at least 10 years. Older individuals have high rates of major vascular events and, given comparable relative risk reductions with lipid-lowering treatments, should therefore have high absolute risk reductions. These results should strengthen guideline recommendations for the use of lipid-lowering treatments, including non-statin therapy, in older patients.
Lancet, 10 listopada 2020