Bowen Tang i wsp. Major depressive disorder and cardiometabolic diseases: a bidirectional Mendelian randomisation study. Diabetologia 2020;63:1305–1311 (dostępny pełen tekst)
The present MR study strengthens the evidence that MDD is a potential risk factor for type 2 diabetes and CAD. However, there was no genetic support for a causal effect of type 2 diabetes or CAD on MDD. Whether MDD is causally related to heart failure needs further investigation. Given the high disease burden related to the causal link, it is recommended that MDD prevention, management and treatment should be enhanced for type 2 diabetes prevention.
Diabetologia, 8 kwietnia 2020