Dożylna witamina C w dużych dawkach w sepsie z zespołem ostrej niewydolności oddechowej – wyniki pilotowego badania CITRIS-ALI

Alpha A. Fowler III i wsp. Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory FailureThe CITRIS-ALI Randomized Clinical Trial. JAMA. 2019;322(13):1261-1270 (dostępny pełen tekst)

CONCLUSIONS AND RELEVANCE:  In this preliminary study of patients with sepsis and ARDS, a 96-hour infusion of vitamin C compared with placebo did not significantly improve organ dysfunction scores or alter markers of inflammation and vascular injury. Further research is needed to evaluate the potential role of vitamin C for other outcomes in sepsis and ARDS.

JAMA Internal Medicine, 1 października 2019

Dodaj komentarz