Inhibitory ACE a sartany: wpływ na rokowanie w nadciśnieniu tętniczym. Analiza z uwzględnieniem wskaźnika NNT

Jasper J. Brugts i wsp. Impact of renin-angiotensin system inhibitors on mortality and major cardiovascular endpoints in hypertension: A number-needed-to-treat analysis , LINK: Int J Cardiol online

Results for cardiovascular mortality (NNT 116 for ACE inhibitors and 409 for ARBs, respectively) and myocardial infarction (NNT 80 and 338, respectively) also appeared to be driven by ACE inhibitors …

Conclusion: Among hypertensive patients, ACE inhibitors but not ARBs, substantially reduce all-cause and cardiovascular mortality and myocardial infarction.

Opracowane na podstawie: Internet / 26 listopada 2014