Otyłość z prawidłowym profilem metabolicznym – czy wiąże się ze wzrostem ryzyka sercowo-naczyniowego? Metaanaliza

Caroline K. Kramer i wsp. Are Metabolically Healthy Overweight and Obesity Benign Conditions?: A Systematic Review and Meta-analysis , LINK: Ann Intern Med. 2013;159:758

Data Synthesis: Eight studies (n = 61 386; 3988 events) evaluated participants for all-cause mortality and/or cardiovascular events. Metabolically healthy obese individuals (relative risk [RR], 1.24; 95% CI, 1.02 to 1.55) had increased risk for events compared with metabolically healthy normal-weight individuals when only studies with 10 or more years of follow-up were considered.

Conclusion: Compared with metabolically healthy normal-weight individuals, obese persons are at increased risk for adverse long-term outcomes even in the absence of metabolic…

Opracowane na podstawie: Annals of Internal Medicine / 3 grudnia 2013