Skuteczność i bezpieczeństwo statyn w długoterminowej perspektywie – 11-letnia obserwacja uczestników Heart Protection Study

Heart Protection Study Collaborative Group – Effects on 11-year mortality and morbidity of lowering LDL cholesterol with simvastatin for about 5 years in 20 536 high-risk individuals: a randomised controlled trial Lancet online
Interpretation:

More prolonged LDL-lowering statin treatment produces larger absolute reductions in vascular events. Moreover, even after study treatment stopped in HPS, benefits persisted for at least 5 years without any evidence of emerging hazards. These findings provide further support for the prompt initiation and long-term continuation of statin treatment.

Opracowane na podstawie: Lancet online / 23 listopada 2011