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The Action to Control Cardiovascular Risk in Diabetes Study Group – Effects of Intensive Glucose Lowering in Type 2 Diabetes Published at www.nejm.org June 6, 2008 (10.1056/NEJMoa0802743)

Conclusions: As compared with standard therapy, the use of intensive therapy to target normal glycated hemoglobin levels for 3.5 years increased mortality and did not significantly reduce major cardiovascular events. These findings identify a previously unrecognized harm of intensive glucose lowering in high-risk patients with type 2 diabetes. (ClinicalTrials.gov number, NCT00000620 [ClinicalTrials.gov] .)

Opracowane na podstawie: Published at www.nejm.org June 6, 2008 (10.1056/NEJMoa0802743)/ 2008-06-06